Essentials of Organic Chemistry: For Students of Pharmacy, Medicinal Chemistry and Biological ChemistryJohn Wiley & Sons, 2006 M05 26 - 710 pages Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry. |
Contents
Atomic structure and bonding | 19 |
Resonance structures and curly arrows | 45 |
3 | 51 |
Configurational isomers with several chiral centres | 85 |
and L configurations | 103 |
4 | 121 |
4 | 135 |
6 | 141 |
Electrophilic reactions | 283 |
Radical reactions | 319 |
Nucleophilic reactions involving enolate anions | 347 |
Heterocycles | 403 |
Carbohydrates | 463 |
Amino acids peptides and proteins | 499 |
Nucleosides nucleotides and nucleic acids | 549 |
The organic chemistry of intermediary metabolism | 573 |
Other editions - View all
Essentials of Organic Chemistry: For Students of Pharmacy, Medicinal ... Paul M. Dewick Limited preview - 2013 |
Essentials of Organic Chemistry: For Students of Pharmacy, Medicinal ... Paul M. Dewick No preview available - 2006 |
Common terms and phrases
acetal acid pKa acyl alcohol aldehyde aldol reaction alkene alkyl allylic amide amine amino acid anhydride atom benzene carbon carbonyl carbonyl group carboxylic acid cation CH2OH CH3 CH3 CH3 H charge chiral centre chloride Claisen reaction CO2 H CO2Et CO2H compounds configuration conformer conjugate acid conjugate base cyclic derivatives diphosphate double bond electrons electrophilic addition enamine enantiomer energy enolate anion enzyme equilibrium ester favourable formation glucose H CH3 H H H H3C CH3 halide hemiacetal heterocycles hydride hydrogen hydrolysis hydroxyl imidazole imine inductive effect intermediate involves ionization isomer ketone leaving group lone pair mechanism methyl molecule nitrogen nucleophilic attack OH H OH OH OH orbitals oxidation oxygen peptide phenol phosphate pKa values planar protein proton pyridine pyrrole racemic radical react reactive reagent resonance stabilization ring system SCoA Section sequence SN2 reaction substituents substrate sugar synthesis tautomer tautomerism tertiary carbocation