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Page 1206
FUS / TLS mutations in ALS cases , with onset and disease duration data . Base numbering begins with the start codon ; amino acid numbering begins with the methionine start codon . Age onset ( years ) Mean ± SD 45.0 ± 3.6 39.6 ± 13.3 65 ...
FUS / TLS mutations in ALS cases , with onset and disease duration data . Base numbering begins with the start codon ; amino acid numbering begins with the methionine start codon . Age onset ( years ) Mean ± SD 45.0 ± 3.6 39.6 ± 13.3 65 ...
Page 1209
Fourteen missense TDP - 43 mutations have now been associated with ALS , and all but one reside in the C - terminal domain ( 7,14-16 ) . In addition , individual FALS kindreds have been linked to chromosomes 18q ( ALS3 , OMIM 606640 ) ...
Fourteen missense TDP - 43 mutations have now been associated with ALS , and all but one reside in the C - terminal domain ( 7,14-16 ) . In addition , individual FALS kindreds have been linked to chromosomes 18q ( ALS3 , OMIM 606640 ) ...
Page 1308
Viroids can tolerate such elevated per - site mutation rates owing to their minimal genomes , whereas more complex genomes would accumulate an excessive mutational utation rates vary by orders of magnihead mutations sampled in vivo ...
Viroids can tolerate such elevated per - site mutation rates owing to their minimal genomes , whereas more complex genomes would accumulate an excessive mutational utation rates vary by orders of magnihead mutations sampled in vivo ...
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Contents
Beyond the Stimulus | 983 |
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