Science, Volume 323, Issues 5917-5922American Association for the Advancement of Science, 2009 |
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Page 1022
... SIRT1 overexpression enhances the ability of cul- tured cells to survive prolonged exposure to lethal heat shock temperatures . SIRT1 there- fore functions as a positive cofactor of HSF1 and enhances the heat shock response . Aging and ...
... SIRT1 overexpression enhances the ability of cul- tured cells to survive prolonged exposure to lethal heat shock temperatures . SIRT1 there- fore functions as a positive cofactor of HSF1 and enhances the heat shock response . Aging and ...
Page 1064
... SIRT1 Mock SIRT1 FOXO , p53 , NFκB Longevity. other cellular protective pathways ( 7 ) . We therefore tested whether the sirtuins , specifi- cally SIRT1 , regulate HSF1 activity and there- by provide a direct link between these three ...
... SIRT1 Mock SIRT1 FOXO , p53 , NFκB Longevity. other cellular protective pathways ( 7 ) . We therefore tested whether the sirtuins , specifi- cally SIRT1 , regulate HSF1 activity and there- by provide a direct link between these three ...
Page 1065
Mock SIRT1 Mock SIRT1 FOXO , p53 , NFκB Longevity Stress resistance Protein homeostasis z ( cm ) 0.8 0.6 0.4 A 0 0.5. therefore investigated SIRT1 as a candidate for regulation of the HSR . When SIRT1 was de- pleted by small interfering ...
Mock SIRT1 Mock SIRT1 FOXO , p53 , NFκB Longevity Stress resistance Protein homeostasis z ( cm ) 0.8 0.6 0.4 A 0 0.5. therefore investigated SIRT1 as a candidate for regulation of the HSR . When SIRT1 was de- pleted by small interfering ...
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acid activity AMPAR analysis aphid applications associated astrocytes behavior Bioinformatics Biol Biology Bmp4 Cancer carbon caspase Cell Biology cells Center Chemistry climate Colby-Sawyer College complex David disease disgust drug dynamics E-mail effect electron energy Engineering environmental enzymes experience expression Fermi surface function gene genetic genome global heat shock HSF1 human imaging increase indicated Institute interactions kinetochore Lett levels magnetic mechanisms Medical membrane meropenem mice million molecular mutations National neurons Neurosci NH Chair observed Ocean pathway Phys Plant Pol IV position postdoctoral potential production protein proteomics ratio receptors References and Notes region regulation response ribozyme RIG-I sample says Science scientific scientists sequence signal SIRT1 species structure substrate Supporting Online Material surface SWNTs target Technology temperature tion transcription Univ University vesicles Vice Chair Waterville Valley Resort