Science, Volume 291John Michels (Journalist) American Association for the Advancement of Science, 2001 |
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Page 872
... cells do not exhibit a senescent. In contrast to germ cells and certain stem cells , most somatic cell types are thought to have a limited proliferative life - span . This limit may have evolved as a protective mechanism against cancer ...
... cells do not exhibit a senescent. In contrast to germ cells and certain stem cells , most somatic cell types are thought to have a limited proliferative life - span . This limit may have evolved as a protective mechanism against cancer ...
Page 873
... cells at any passage ( represented by p.10 , lower panel ) did not express detectable SA - B - Gal activity . Schwann cells were treated with aphidicolin ( 1 μg / ml ) for 5 days or cultured continuously for 2 to 3 weeks in Schwann cell ...
... cells at any passage ( represented by p.10 , lower panel ) did not express detectable SA - B - Gal activity . Schwann cells were treated with aphidicolin ( 1 μg / ml ) for 5 days or cultured continuously for 2 to 3 weeks in Schwann cell ...
Page 874
... cells and fibroblasts revealed differences between the two cell types . In particular , Schwann cells expressed much higher levels of cyclin D1 , Cdk - 4 , and Cdk - 2 than did the fibroblasts ( Fig . 3C ) . The higher levels of cyclins ...
... cells and fibroblasts revealed differences between the two cell types . In particular , Schwann cells expressed much higher levels of cyclin D1 , Cdk - 4 , and Cdk - 2 than did the fibroblasts ( Fig . 3C ) . The higher levels of cyclins ...
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