Science, Volume 311, Issues 5763-5769John Michels (Journalist) 2006 |
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Page 1014
... sumoylation at Lys 40 MEF2's transcriptional repression function . First , we demonstrated that MEF2A Lys 403 is mod- 403 and ified by sumoylation in vitro and in cells ( Fi 3C ; fig . S6 ) . Interestingly , MEF2A was al acetylated in ...
... sumoylation at Lys 40 MEF2's transcriptional repression function . First , we demonstrated that MEF2A Lys 403 is mod- 403 and ified by sumoylation in vitro and in cells ( Fi 3C ; fig . S6 ) . Interestingly , MEF2A was al acetylated in ...
Page 1015
... sumoylation , which indicates that Lys403 is a bona fide SUMO acceptor site ( 24 ) . ( D ) Calcineurin inhibits sumoylation and promotes acetylation of MEF2A . Cells transfected with G4 - MEF2A and HA - CnA * were analyzed as in ( C ) ...
... sumoylation , which indicates that Lys403 is a bona fide SUMO acceptor site ( 24 ) . ( D ) Calcineurin inhibits sumoylation and promotes acetylation of MEF2A . Cells transfected with G4 - MEF2A and HA - CnA * were analyzed as in ( C ) ...
Page 1016
... sumoylation and acet- ylation in transcription factors may play a widespread role in signal - regulated transcription and regulate diverse biological processes , includ- ing synapse development and plasticity . References and Notes 1 ...
... sumoylation and acet- ylation in transcription factors may play a widespread role in signal - regulated transcription and regulate diverse biological processes , includ- ing synapse development and plasticity . References and Notes 1 ...
Contents
Revised Numbers Quicken the Pace of Rebound | 931 |
A Protein Farnesyltransferase Inhibitor Ameliorates Disease | 934 |
Report p 1005 | 937 |
Copyright | |
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AAAS acid activity animals antibodies apoptosis applications areas asexual Ash1 assay associated Biol biology blastocyst blastomere calcineurin Cancer candidates Cdx2 cell biology Center chromatin chromosome clinical clusters collaborative complex curriculum vitae dendritic claw Department detected Director disease drug E-mail electron embryos engineering evolution experience expression faculty female function funding gene genetic genomic Geophys glaciers global granule neurons Greenland Health human images increase Institute interactions laboratory Mbar Medical Medicine MEF2 MEF2A mice molecular moons mouse mutations National NEMO neurons neuroscience observed oocytes orbits patent Ph.D phosphorylation plasmid player population position postdoctoral Professor protein regulation research program response Rev-erba rings RNAi role says School Science scientific scientists sexual signaling siRNA species stem cells sumoylation synapses target threat point tion transcription transcription factor transfected Univ University virus X chromosome