Science, Volume 311, Issues 5763-5769John Michels (Journalist) 2006 |
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Page 1010
... calcineurin ( PP2B ) has been implicated in the activity- dependent dephosphorylation of MEF2 ( 12 ) . Using the specific inhibitors of calcineurin , cyclosporin A ( CSA ) and FK506 , we observed that the membrane depolarization ...
... calcineurin ( PP2B ) has been implicated in the activity- dependent dephosphorylation of MEF2 ( 12 ) . Using the specific inhibitors of calcineurin , cyclosporin A ( CSA ) and FK506 , we observed that the membrane depolarization ...
Page 1014
... calcineurin might , therefore , control postsynaptic dendritic differ- entiation via a MEF2 - regulated transcriptional mechanism . We first determined the site of calcineurin- mediated dephosphorylation of MEF2A . Because calcineurin ...
... calcineurin might , therefore , control postsynaptic dendritic differ- entiation via a MEF2 - regulated transcriptional mechanism . We first determined the site of calcineurin- mediated dephosphorylation of MEF2A . Because calcineurin ...
Page 1015
... Calcineurin dephosphorylates MEF2A Ser 408. Lysates of 293T cells transfected with MEF2A and hemagglutinin ( HA ) -tagged constitutively active calcineurin subunit A ( HA - CnA * ) or control vector were immuno- blotted for MEF2A ...
... Calcineurin dephosphorylates MEF2A Ser 408. Lysates of 293T cells transfected with MEF2A and hemagglutinin ( HA ) -tagged constitutively active calcineurin subunit A ( HA - CnA * ) or control vector were immuno- blotted for MEF2A ...
Contents
Revised Numbers Quicken the Pace of Rebound | 931 |
A Protein Farnesyltransferase Inhibitor Ameliorates Disease | 934 |
Report p 1005 | 937 |
Copyright | |
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AAAS acid activity animals antibodies apoptosis applications areas asexual Ash1 assay associated Biol biology blastocyst blastomere calcineurin Cancer candidates Cdx2 cell biology Center chromatin chromosome clinical clusters collaborative complex curriculum vitae dendritic claw Department detected Director disease drug E-mail electron embryos engineering evolution experience expression faculty female function funding gene genetic genomic Geophys glaciers global granule neurons Greenland Health human images increase Institute interactions laboratory Mbar Medical Medicine MEF2 MEF2A mice molecular moons mouse mutations National NEMO neurons neuroscience observed oocytes orbits patent Ph.D phosphorylation plasmid player population position postdoctoral Professor protein regulation research program response Rev-erba rings RNAi role says School Science scientific scientists sexual signaling siRNA species stem cells sumoylation synapses target threat point tion transcription transcription factor transfected Univ University virus X chromosome