Destruction of Hazardous Chemicals in the Laboratory

Front Cover
John Wiley & Sons, 2012 M05 1 - 800 pages
The book describes practical procedures for the destruction of hazardous chemicals and biological agents in the laboratory in which they are used. The book is a continuation and expansion of “Destruction of Hazardous Chemicals in the Laboratory.” It follows the same general approach as the first and second editions but includes a number of new chapters including one on using advanced oxidation techniques as a general means of degrading chemicals. All the monographs from the second edition are incorporated in this volume and are revised and extended as necessary.  A number of new monographs describing procedures for the destruction of hazardous chemicals have also been added.

The destruction of many pharmaceuticals is also described in this book. This subject has become of increasing importance with recent reports of the detection of pharmaceuticals in the water supply. Finally a new addition is the chapter “General Methods for the Destruction of Hazardous Chemicals in the Laboratory.” This chapter describes recent advanced oxidation methods that should be generally applicable to all organic compounds.  The methods use commonly available laboratory equipment and reagents.

 

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Contents

Destruction Procedures5
Related Compounds
Principle of Destruction
Principles of Destruction
Destruction Procedures
Analytical Procedures22
Reagents
Principles of Destruction

Principle of Destruction
Analytical Procedures21
Principles of Destruction
Destruction Procedures
Analytical Procedures
Related Compounds
Principles of Destruction
Principle of Destruction
Principles of Destruction
Analytical Procedures
Principles of Destruction
Analytical Procedures
Mutagenicity Assays20 32
Principles of Decontamination
Analytical Procedures
Principles of Destruction
Destruction Procedures
Analytical Procedures
Related Compounds and Reactions
Principles of Destruction
Destruction Procedures
Analytical Procedures
Mutagenicity Assays
Related Compounds
Principles of Destruction and Decontamination
Destruction and Decontamination Procedures10
Related Compounds
Principles of Destruction
Detection Procedures
Principles of Destruction
Destruction Procedures
Assay of Sodium Hypochlorite Solution
Principle of Destruction
Analytical Procedures for Alkyllithium Reagents
Destruction Procedures
Principles of Destruction
Destruction Procedures
Mutagenicity Assays
Principles of Destruction and Decontamination
Analytical Procedures
Destruction Procedure6 7
Destruction Procedure8
Destruction Procedure4
Principles of Destruction
Destruction Procedures
Analytical Procedures
Related Compounds and Related Procedures
Principle of Destruction
Destruction Procedures7
Analytical Procedures
Assay of Sodium Hypochlorite Solution
Principles of Destruction
Destruction Procedures
Assay of Sodium Hypochlorite Solution
Related Compounds
Principles of Destruction
Destruction Procedures
Assay of Sodium Hypochlorite Solution
Mutagenicity Assays
Principle of Destruction
Analytical Procedures
Principle of Destruction
Destruction Procedures15
Buffers
Procedure
Mutagenicity Assays
Principles of Destruction
Destruction Procedures
Analytical Procedures7 28
Mutagenicity Assays
Related Compounds
Principles of Decontamination and Destruction
Decontamination Procedures16 20
Destruction Procedures
Analytical Procedures
Mutagenicity Assays16 20
Principles of Destruction and Decontamination
Destruction and Decontamination Procedures
Buffer Solutions
Mutagenicity Assays
Alternatives
Principles of Destruction
Analytical Procedures
Mutagenicity Assays
Principles of Destruction
Destruction Procedures36
Analytical Procedures
Mutagenicity Assays
Principle of Destruction
Principles of Decontamination
Decontamination Procedures
Analytical Procedures
Principle of Destruction
Mutagenicity Assays
Principles of Destruction
Assay of Sodium Hypochlorite Solution
Analytical Procedures
Related Compounds
Principle of Destruction
Assay of Hypochlorites
Principles of Decontamination
Decontamination Procedures
Analytical Procedures
Principle of Destruction
Mutagenicity Assays
Principles of Destruction
Destruction Procedures
Preparation of MPTP Tartrate5
Mutagenicity Assays
Principles of Destruction
Destruction Procedures
Related Compounds and Related Procedures
Principle of Destruction
Mutagenicity Assays
Principles of Destruction5
Analytical Procedures
Related Compounds
Principle of Destruction
Analytical Procedures
Assay of Sodium Hypochlorite Solution
Principle of Destruction
Related Compounds
Principle of Decontamination
Analytical Procedures
Principle of Destruction
Analytical Procedures
Principles of Destruction
Analytical Procedures
Destruction Procedure5
Principles of Destruction and Decontamination
Analytical Procedures
Related Compounds and Procedures
Principles of Destruction
Analytical Procedures
Principles of Decontamination
Related Compounds and Related Procedures
Principle of Destruction
Analytical Procedure8
Principles of Destruction
Assay of Sodium Hypochlorite Solution
Principles of Destruction
Analytical Procedures4
Principles of Destruction
Destruction Procedures
Analytical Procedures
Mutagenicity Assays1
Principles of Destruction
Analytical Procedures
Mutagenicity Assays1
Principle of Destruction
Principle of Destruction
Mutagenicity Assays
Principle of Destruction8
Destruction Procedures8
Analytical Procedures8
Mutagenicity Assays8
Principles of Destruction
Analytical Procedures
Principles of Destruction
Destruction Procedures
Related Compounds
Principles of Decontamination
Destruction Procedure2 3
Principles of Destruction
Analytical Procedures2
Assay of Sodium Hypochlorite Solution
Principle of Destruction9
Destruction Procedures9
Analytical Procedures9
Related Compounds
Principle of Destruction
Destruction Procedures22
Assay of Sodium Hypochlorite Solution
Related Compounds and Related Procedures
Principles of Destruction
Destruction Procedure
Related Compounds
Principles of Destruction
Analytical Procedures
Principles of Destruction and Decontamination
Destruction Procedures
Related Compounds
Principle of Decontamination
Analytical Procedures
Analytical Procedures
Principles of Destruction
Destruction Procedures
Analytical Procedures
Related Compounds
Principles of Destruction
Destruction Procedures
Analytical Procedures
Mutagenicity Assays
Principles of Destruction
Destruction Procedures
Analytical Procedures
Mutagenicity Assays
Related Compounds
Principles of Destruction
Related Compounds
Principles of Destruction
Related Compounds
Principles of Destruction
Related Compounds
Principle of Destruction
Principles of Destruction
Related Compounds
Principles of Destruction
Principles of Destruction
Destruction Procedures
Analytical Procedures
Mutagenicity Assays
Principles of Destruction
Destruction Procedures
Related Reactions
Mutagenicity Assays
Principles of Destruction
Related Compounds
Potassium Permanganate Oxidation
Recommended Potassium Permanganate Degradation Procedures
Advanced Oxidation Processes
Photolysis
Procedures for Drying Organic Solvents
Safety Considerations with Potassium Permanganate
Reactions Involving 3 M Sulfuric Acid
Reactions Involving 1 M Sodium Hydroxide and Water
Conclusions
Recommended Degradation Procedures
Copyright

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About the author (2012)

George Lunn, PhD, has been working as a review chemist for the FDA's Office of New Drug Quality Assessment since 1996. Previously, he was a senior research scientist in the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center. He has written nine books and over sixty papers and review articles.

Eric B. Sansone, PhD, was the director of the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center until his retirement. He has also worked as a consultant in industrial hygiene and air pollution control for a widely diversified group of industries, law firms, universities, and governmental agencies. He has published many articles on the assessment of risk in cancer research.

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