Destruction of Hazardous Chemicals in the Laboratory

Front Cover
John Wiley & Sons, 2012 M05 1 - 800 pages
The book describes practical procedures for the destruction of hazardous chemicals and biological agents in the laboratory in which they are used. The book is a continuation and expansion of “Destruction of Hazardous Chemicals in the Laboratory.” It follows the same general approach as the first and second editions but includes a number of new chapters including one on using advanced oxidation techniques as a general means of degrading chemicals. All the monographs from the second edition are incorporated in this volume and are revised and extended as necessary. A number of new monographs describing procedures for the destruction of hazardous chemicals have also been added.

The destruction of many pharmaceuticals is also described in this book. This subject has become of increasing importance with recent reports of the detection of pharmaceuticals in the water supply. Finally a new addition is the chapter “General Methods for the Destruction of Hazardous Chemicals in the Laboratory.” This chapter describes recent advanced oxidation methods that should be generally applicable to all organic compounds. The methods use commonly available laboratory equipment and reagents.

 

Contents

Acetonitrile
19
Aflatoxins
29
Alkali and Alkaline Earth Metals
37
AnatoxinA
43
Arsenic
57
Azides
61
Boron Trifluoride and Inorganic Fluorides
77
Calcium Carbide
93
Organic Nitriles
327
Peracids
347
Phosgene
363
Polycyclic Heterocyclic Hydrocarbons
387
Potassium Permanganate
405
Saxitoxin
421
Sulfonyl Fluoride Enzyme Inhibitors
437
Tetrodotoxin
455

ChromiumVI
107
Complex Metal Hydrides
121
Cylindrospermopsin
137
Dimethyl Sulfate and Related Compounds
151
Ethidium Bromide
201
Haloethers
211
Halogens
229
Hydrazines
245
Mercury
261
Microcystins
277
Nitrogen Tetroxide
291
Nitrosamines
307
General Considerations
469
Potassium Permanganate
549
Sodium Hypochlorite
567
Fentons Reagent
583
Hydroxylamine Degradation of βLactams
603
Decontamination of Aqueous Solutions
627
Procedures for Drying Organic Solvents
657
MOLECULAR FORMULA INDEX
671
CROSS INDEX OF PHARMACEUTICAL NAMES
693
CROSSINDEX OF NAMES FOR DYES AND BIOLOGICAL
729
NAME INDEX
757
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About the author (2012)

GEORGE LUNN, PHD, has been working as a review chemist for the FDA's Office of New Drug Quality Assessment since 1996. Previously, he was a senior research scientist in the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center. He has written nine books and over sixty papers and review articles.

ERIC B. SANSONE, PHD, was the director of the Environmental Control and Research Program at the NCI-Frederick Cancer Research and Development Center until his retirement.?? He has also worked as a consultant in industrial hygiene and air pollution control for a widely diversified group of industries, law firms, universities, and governmental agencies. He has published many articles on the assessment of risk in cancer research.

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