Science, Volume 292John Michels (Journalist) American Association for the Advancement of Science, 2001 |
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Results 1-3 of 80
Page 111
... activity in vitro ( 19 ) . To determine whether the conserved domains , the chromo , SET , and cysteine - rich regions , were also critical for Clr4 HMTase activity , we tested mutant Clr4 proteins for HMTase activity . Although ...
... activity in vitro ( 19 ) . To determine whether the conserved domains , the chromo , SET , and cysteine - rich regions , were also critical for Clr4 HMTase activity , we tested mutant Clr4 proteins for HMTase activity . Although ...
Page 112
... activity and that Clr4 appears to be the ex- clusive in vivo H3 Lys - specific HMTase at mat and cen loci . In comparison with our in vitro result showing that only the SET do- main is required for Clr4 HMTase activity ( Fig . 1B ) , we ...
... activity and that Clr4 appears to be the ex- clusive in vivo H3 Lys - specific HMTase at mat and cen loci . In comparison with our in vitro result showing that only the SET do- main is required for Clr4 HMTase activity ( Fig . 1B ) , we ...
Page 470
... activity when it was pretreated with mammalian cell extract supple- mented with Fe ( II ) ( Fig . 3 , B and C ) . Overall , no peptide could block the interaction without prior enzymatic modification , blocking activity could not be ...
... activity when it was pretreated with mammalian cell extract supple- mented with Fe ( II ) ( Fig . 3 , B and C ) . Overall , no peptide could block the interaction without prior enzymatic modification , blocking activity could not be ...
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activity analysis antibodies applications areas assay biochemistry bioinformatics biopterin Cancer candidate Cell Biology Center changes Chemistry chico climate clinical clones Clr4 CO₂ curriculum vitae Department disease drug discovery E-mail ecosystems effects environment Equal Opportunity Employer experience function gene Genetics genomics global habitat histone histone H3 human increase input Institute interactions Invitrogen isolates kangaroo rats laboratory layer levels life-span Medical Medicine ment methoprene methylation molecular biology molecules mutants National Nature neurons Neurosci nitrification Novartis observed ocean particles pathway peptides PerkinElmer Ph.D pharmaceutical Phys polymer POSTDOCTORAL POSITION production protein proteomics reagent RecQ helicases refraction response sample says Science scientific scientists send curriculum vitae sequence Service Card signal signal transduction species StatSoft stream structure superconducting surface Swi6 temperature three references tion transgenic trees Univ University uptake wild-type