Science, Volume 292John Michels (Journalist) American Association for the Advancement of Science, 2001 |
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Page 229
... RecQ family of DNA helicases ( 1 ) . Remarkably , defects in two other human RecQ family members give rise to disorders character- ized by cancer predisposition and prema- ture aging : The WRN protein is defective in Werner's syndrome ...
... RecQ family of DNA helicases ( 1 ) . Remarkably , defects in two other human RecQ family members give rise to disorders character- ized by cancer predisposition and prema- ture aging : The WRN protein is defective in Werner's syndrome ...
Page 230
... RecQ helicases achieve the apparently conflicting tasks of both promoting HR and suppressing " promiscuous " HR is not yet clear . One possibility is that they are able to influence the choice of template DNA used during recombination ...
... RecQ helicases achieve the apparently conflicting tasks of both promoting HR and suppressing " promiscuous " HR is not yet clear . One possibility is that they are able to influence the choice of template DNA used during recombination ...
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