Science, Volume 316John Michels (Journalist) Science Company, Moses King, 2007 A weekly record of scientific progress. |
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Page 755
... CARMA1 ( 17 , 18 ) . In unstimu- lated ADAP or ADAPT cells , only low levels of BCL - 10 and MALT1 were detected in membrane fractions ( Fig . 3A ) . CD3 / CD28 or PMA stimulation of ADAP + T cells , but not B 10.0- Fold increase in p65 ...
... CARMA1 ( 17 , 18 ) . In unstimu- lated ADAP or ADAPT cells , only low levels of BCL - 10 and MALT1 were detected in membrane fractions ( Fig . 3A ) . CD3 / CD28 or PMA stimulation of ADAP + T cells , but not B 10.0- Fold increase in p65 ...
Page 756
... CARMA1 Cyto 430 BCL - 10 MALT1 Memb ◅30 BCL - 10 111 Cyto MALT1 111 C Memb + ctrl Cyto CARMA1 111 BCL - 10 Memb 111 MALT1 CARMA1 ADAP D GST- GST ADAP IP : BCL - 10 ADAP + / + ADAP - / - ADAP - / - + ctrl + ADAPwt U 3/28 P U 3/28 P U ...
... CARMA1 Cyto 430 BCL - 10 MALT1 Memb ◅30 BCL - 10 111 Cyto MALT1 111 C Memb + ctrl Cyto CARMA1 111 BCL - 10 Memb 111 MALT1 CARMA1 ADAP D GST- GST ADAP IP : BCL - 10 ADAP + / + ADAP - / - ADAP - / - + ctrl + ADAPwt U 3/28 P U 3/28 P U ...
Page 757
... CARMA1 association and TCR - dependent A ADAP wt 328 ADAPA1-327 activation of NF - κB , but is dis- ADAP - 426 ... CARMA1 may also alter intramolecular in- teractions within CARMA1 ( 25 , 26 ) , thereby promoting recruitment of BCL ...
... CARMA1 association and TCR - dependent A ADAP wt 328 ADAPA1-327 activation of NF - κB , but is dis- ADAP - 426 ... CARMA1 may also alter intramolecular in- teractions within CARMA1 ( 25 , 26 ) , thereby promoting recruitment of BCL ...
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ABI4 activation ADAP analysis applications associated atoms Biol biology blastocyst blastomeres Cancer candidate CARMA1 cell biology cells chloroplast climate clinical CO₂ complex coral core density Desertification disease drylands E-Ab axis E-mail Earth Planet electron transfer embryos emissions energy environmental experience gene genetic genomic genotype Geophys global growth GUN1 gun5 hAPP hAPP/Tau Health heliopause human increase indicate Institute interactions interstellar ions ip IPSCs IPSCs kainate receptors kinetic Laboratory Lett levels Lhcb libration magnetic field measurements Medical mice models molecular molecules mutants nanospheres nanowires National neurons Notch Notch signaling observed pathway photons Phys PIP3 piRNAs Plant plasma position potential protein pyramidal qubit reaction centers receptors reefs region says scale Science scientists signaling species studies superfluidity surface tau reduction Technology temperature THH Pt NCs tholins thymosin tion ultracold Univ University