Science, Volume 316John Michels (Journalist) Science Company, Moses King, 2007 A weekly record of scientific progress. |
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Page 755
... ADAP +/- ADAP - / - unstim . unstim . Frequency unstim . CD3 / CD28 CD3 / CD28 31 6 affected by loss of ADAP ( Fig . 2E ) . Activa- tion of the IκB kinase ( IKK ) complex , which phosphorylates IκBa , was also impaired after CD3 / CD28 ...
... ADAP +/- ADAP - / - unstim . unstim . Frequency unstim . CD3 / CD28 CD3 / CD28 31 6 affected by loss of ADAP ( Fig . 2E ) . Activa- tion of the IκB kinase ( IKK ) complex , which phosphorylates IκBa , was also impaired after CD3 / CD28 ...
Page 756
... ADAP +/- ADAP - / - B U 3/28 P U 3/28 P Cyto 111 ADAP Memb Membrane fraction IP : ADAP IP : CARMA1 ADAP +/- ADAP- / ADAP +/- ADAP - / - U 3/28 P U 3/28 P U 3/28 P U 3/28 P 4111 ADAP CARMA1 Cyto 430 BCL - 10 MALT1 Memb ◅30 BCL - 10 ...
... ADAP +/- ADAP - / - B U 3/28 P U 3/28 P Cyto 111 ADAP Memb Membrane fraction IP : ADAP IP : CARMA1 ADAP +/- ADAP- / ADAP +/- ADAP - / - U 3/28 P U 3/28 P U 3/28 P U 3/28 P 4111 ADAP CARMA1 Cyto 430 BCL - 10 MALT1 Memb ◅30 BCL - 10 ...
Page 757
... ADAP : wt 327 426 481 541 541 Fig . 4. The region of ADAP con- taining the N - terminal helical SH3 domain and an E / K - rich re- gion is critical for ADAP - CARMA1 association and TCR - dependent A ADAP wt 328 ADAPA1-327 activation of ...
... ADAP : wt 327 426 481 541 541 Fig . 4. The region of ADAP con- taining the N - terminal helical SH3 domain and an E / K - rich re- gion is critical for ADAP - CARMA1 association and TCR - dependent A ADAP wt 328 ADAPA1-327 activation of ...
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ABI4 activation ADAP analysis applications associated atoms Biol biology blastocyst blastomeres Cancer candidate CARMA1 cell biology cells chloroplast climate clinical CO₂ complex coral core density Desertification disease drylands E-Ab axis E-mail Earth Planet electron transfer embryos emissions energy environmental experience gene genetic genomic genotype Geophys global growth GUN1 gun5 hAPP hAPP/Tau Health heliopause human increase indicate Institute interactions interstellar ions ip IPSCs IPSCs kainate receptors kinetic Laboratory Lett levels Lhcb libration magnetic field measurements Medical mice models molecular molecules mutants nanospheres nanowires National neurons Notch Notch signaling observed pathway photons Phys PIP3 piRNAs Plant plasma position potential protein pyramidal qubit reaction centers receptors reefs region says scale Science scientists signaling species studies superfluidity surface tau reduction Technology temperature THH Pt NCs tholins thymosin tion ultracold Univ University