Science, Volume 308, Issues 5719-5725John Michels (Journalist) American Association for the Advancement of Science, 2005 |
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Page 368
... tetracycline antibiotics . ( Center ) Tetracyclines are composed of four fused rings , designated A , B , C , and D. They bind to 30S ribosomal subunits from most bacteria , primarily via contacts at the southern and eastern faces ...
... tetracycline antibiotics . ( Center ) Tetracyclines are composed of four fused rings , designated A , B , C , and D. They bind to 30S ribosomal subunits from most bacteria , primarily via contacts at the southern and eastern faces ...
Page 395
... tetracycline antibiotics . ( - ) - Tetracycline ( 1 ) was first produced semisynthetically , by hydrogenolysis of the fermentation product aureomycin ( 7 - chlorotetracycline ) , but later was discovered to be a natural product and is ...
... tetracycline antibiotics . ( - ) - Tetracycline ( 1 ) was first produced semisynthetically , by hydrogenolysis of the fermentation product aureomycin ( 7 - chlorotetracycline ) , but later was discovered to be a natural product and is ...
Page 396
... tetracycline itself from the A- ring precursor D - glucosamine ( 34 steps , 0.002 % yield ) ( 16 ) . The most efficient construction of the tetracycline ring system thus far is the synthesis of ( + ) - 12a - deoxytetracycline by the ...
... tetracycline itself from the A- ring precursor D - glucosamine ( 34 steps , 0.002 % yield ) ( 16 ) . The most efficient construction of the tetracycline ring system thus far is the synthesis of ( + ) - 12a - deoxytetracycline by the ...
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activity alkyne metathesis anorthite antibodies antigen applications areas associated assortative mating axon binding Biol biology bivoltine CAIS Cancer Research candidates cap carbonates carbon cell biology cell-cell fusion Center Chem clinical complex copolymer coral cross-linked cytokines Department Director disease domain drug E-mail electron embryos endocast evolution experience factor forest function gene genetic genome global gynes human ibogaine imaging Institute interactions isotope KaiC kinase Laboratory Libyan ligand loop material Medical melilite membrane ment mice microtubule million molecular molecules mutant myoblast National neurons nuclear Online oxytocin pathway peptide phosphorylation position protein receptors region sample says Science scientists sea-level sediment sequences signal SNPs specific stem cell structure substrate surface table S1 temperature tetracycline TGOT tion TRAF6 Univ University vasopressin wound response y8 TCR YBCO