Science, Volume 310, Issues 5745-5750John Michels (Journalist) 2005 |
From inside the book
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Page 43
... mutant protein made by the Huntington's gene , researchers have identified several candidate drugs that are starting clinical trials The discovery of the gene that causes a life- threatening disease always sparks a wave of I hope that ...
... mutant protein made by the Huntington's gene , researchers have identified several candidate drugs that are starting clinical trials The discovery of the gene that causes a life- threatening disease always sparks a wave of I hope that ...
Page 44
... mutant Htt in both cultured cells and Huntington's mice . Although the idea that N - terminal frag- ments of mutant Htt are toxic has been gain- ing acceptance , the role of the aggregates remains controversial . Some evidence indi ...
... mutant Htt in both cultured cells and Huntington's mice . Although the idea that N - terminal frag- ments of mutant Htt are toxic has been gain- ing acceptance , the role of the aggregates remains controversial . Some evidence indi ...
Page 861
... ( mutant ) Presynaptic Rescue DCO G + / + Forskolin H syt 4 Forskolin 200 PALL 10 sec Frequency , Hz Frequency , Hz ... mutant [ syt 4BA1 ( B ) ; rn16 showed an indistinguishable phenotype ] but restored in postsynaptically rescued ...
... ( mutant ) Presynaptic Rescue DCO G + / + Forskolin H syt 4 Forskolin 200 PALL 10 sec Frequency , Hz Frequency , Hz ... mutant [ syt 4BA1 ( B ) ; rn16 showed an indistinguishable phenotype ] but restored in postsynaptically rescued ...
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