Science, Volume 298, Issues 5600-5602M. King, 2002 |
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Page 2200
1 Fig . 2. ( A and B ) Differentiation of memory B cells to Ig - secreting cells . ( A ) CFSE - labeled memory B cells were stimulated for 5 days with CpG and IL - 15 , and the expression of CD20 was measured as a function of cell division ...
1 Fig . 2. ( A and B ) Differentiation of memory B cells to Ig - secreting cells . ( A ) CFSE - labeled memory B cells were stimulated for 5 days with CpG and IL - 15 , and the expression of CD20 was measured as a function of cell division ...
Page 2201
... memory B cells that respond to polyclonal activators . To test this , we used enzyme - linked immunospot ( ELISPOT ) assays to measure the frequency of circulating plasma cells secreting general antibodies ( Ig ) or antibodies to ...
... memory B cells that respond to polyclonal activators . To test this , we used enzyme - linked immunospot ( ELISPOT ) assays to measure the frequency of circulating plasma cells secreting general antibodies ( Ig ) or antibodies to ...
Page 2202
... memory B cells have two response modes . In the antigen - dependent mode , they undergo a massive expansion and differenti- ation toward short - lived plasma cells . This response is transient , because of the negative feedback ...
... memory B cells have two response modes . In the antigen - dependent mode , they undergo a massive expansion and differenti- ation toward short - lived plasma cells . This response is transient , because of the negative feedback ...
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