Science, Volume 333, Issues 6039-6044John Michels (Journalist) American Association for the Advancement of Science, 2011 |
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Page 460
... etoposide molecules , and six Mg2 + ions are clearly visible in the electron density maps ( fig . S1 ) . The observation of phosphotyrosyl link- AM 1 B C -8 -7 ATPase 5'- A G C C ages between the two active - site tyrosine residues ...
... etoposide molecules , and six Mg2 + ions are clearly visible in the electron density maps ( fig . S1 ) . The observation of phosphotyrosyl link- AM 1 B C -8 -7 ATPase 5'- A G C C ages between the two active - site tyrosine residues ...
Page 461
... etoposide molecules into two cleavage sites . ( B ) Close - up stereo representation of the etoposide - binding site . that DNA is shown in blue , and two hTOP2ẞcore monomers are colored differently . Labels belonging to the second ...
... etoposide molecules into two cleavage sites . ( B ) Close - up stereo representation of the etoposide - binding site . that DNA is shown in blue , and two hTOP2ẞcore monomers are colored differently . Labels belonging to the second ...
Page 462
... etoposide molecules are needed to stabilize a double - stranded break ( 22 ) . The nonplanar conformation adopted by etoposide , owing to the 1,4 - trans arrangement of the E ring and glycosidic group , strongly sug- gests that its ...
... etoposide molecules are needed to stabilize a double - stranded break ( 22 ) . The nonplanar conformation adopted by etoposide , owing to the 1,4 - trans arrangement of the E ring and glycosidic group , strongly sug- gests that its ...
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